At review time this was basically a proof of concept ("10-30 minutes play time", so take this with a grain of salt; it will likely feel very different as it develops. There's a lot of potential here, but it currently feels quite rough.
For instance, I unlocked the dice tray that autorolls your dice, and thought for several minutes that it was broken. I finally discovered that the tray only activates when you DROP dice, not ROLL them, into the tray bottom. (You have to pick them up and stop moving your mouse for a second before letting the button go.) Selecting dice is fiddly, dice can roll off the screen early, and some of the upgrades are strictly worse than nothing at all -- for instance, "reroll on rolling minimum value", which only activates in the dice tray, but does not allow you to resolve the tray's roll until the rerolled die is picked up and re-thrown into something other than minimum, meaning that you lose out on income for the entire time it's rerolling.
Fortunately, there is an unlockable building to deal with that by deleting the mutation. There's also buildings to do things such as combine and sacrifice dice, and you can upgrade the purchaseable dice and the roller tray. It starts to unfold into a game with some strategic depth, then ends as the interesting decisions start appearing. I think this shows promise if the author can smooth out the UI and then offer more mid- and late-game options to extend the experience.