Create profit by clicking the [profit] button.

Use profit to hire rats. Rats will automatically create profit for you.

Once you have enough profit, use it to buy rat generators in the generators [G] tab. Rat generators create more rats to work for you.

In the boosters [B] tab, you can send rats to work at booster generators. Booster generators create boosters that boost you're profit and rat generation. Boosters are consumed by rats.

At some point the rats will form an union. Union rats will start a strike and refuse to work. The rats on strike will not generate profit for you.

In the revolution [R] tab, you can send rats to work at revolution counter generators. These generators generate revolution counters that will make some of the rats on strike return to work.

In the Prestiege [P] tab, you can reset the game to gain a profit generation bonus.

If you get stuck, you can always give up the current run in the settings [S] tab.

The web version does not save your progression.